Top Life Sciences Private Equity Funds with Recent Private M&A Activity

219

Active Firms

14,476

TTM Deal Inquiries

$3M-$19M

Core Revenue Range

$800K-$4M

Core EBITDA Range

Top States by Activity

Florida 14%

California 11%

Texas 10%

New York 8%

New Jersey 4%

Key Attributes

Focus: Control Investments | Capital Source: Committed Capital | Operating Approach: Scale & Exit

Pine Tree Equity Partners, LLC

2 Total Closed Deals Actively Sourcing Deals

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Pine Tree Equity transforms small capitalization, entrepreneurial success stories into institutional platforms positioned for continued growth.Pine Tree Equity, based in Miami, FL, is a private equity firm focused on the investment in and active expansion of small capitalization companies in partnership with management.We invest in small capitalization companies with $10.0 to $50.0 million of revenue across a variety of industries, including business, consumer and financial services; consumer products; franchisors and franchisees; and niche manufacturing.Pine Tree Equity is focused on high…

Recent Transactions

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Dec 2022 Acquired Marshall & Stevens
Aug 2022 Invested in Atlantix Partners

Novadvice

2 Total Closed Deals Actively Sourcing Deals

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Novadvice is an independent alternative investment boutique focused on enhancing client wealth while generating a positive social impact through exclusive, innovative, and responsible investments. With over 20 years of experience, the firm collaborates with asset managers, fund service providers, real estate experts, and entrepreneurs to select a wide range of investment opportunities. Novadvice is committed to tailoring its products to meet clients' best interests and manages all aspects of the investment process. The company has successfully set up investment vehicles, including acquiring…

Recent Transactions

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May 2025 Acquired Confidential Company
Jan 2025 Acquired Confidential Company

Gemspring Capital

2 Total Closed Deals Actively Sourcing Deals

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With $350 million of committed capital under management, Gemspring Capital is a private equity firm specializing in lower middle market companies. We provide flexible capital and partner with talented management teams to propel companies to grow and achieve their full potential. At Gemspring, we take a hands-on approach to investing and commit operating and strategic resources to help drive revenue growth and operating efficiencies at each of our portfolio companies. We take smart risks with capital investment and often pursue transformational add-on acquisitions. The goal for each…

Recent Transactions

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Jun 2017 Acquired Therma
Dec 2016 Acquired United Group Programs

Paradigm Equity Partners

1 Total Closed Deal Actively Sourcing Deals

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Paradigm Equity Partners is a Los Angeles-based private equity firm focused on acquiring companies in the lower middle-market. Our experience is working in complex, time sensitive situations where companies benefit from a capital infusion and operational improvements. We focus on sectors where we have experience and seek to partner with management teams with a track record of success and a desire to execute on well-defined margin-expansion and growth initiatives.

Recent Transactions

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Dec 2023 Acquired E&R Industrial Sales

SaaS Wealth Fund, LLC.

1 Total Closed Deal Actively Sourcing Deals

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We invest in high-quality, founder-led B2B companies with recurring or repeatable revenue — including SaaS, MSPs, and service-based businesses. Whether you're looking to fully exit, de-risk, or accelerate growth, we bring more than just capital. We offer a tailored, founder-aligned approach designed to protect your legacy, support your team, and unlock the next stage of growth on your terms.

Recent Transactions

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Oct 2020 Acquired Confidential Company

STAPLE Investments

1 Total Closed Deal Actively Sourcing Deals

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Staple Investments is a private equity firm dedicated to long-term investments and fostering business growth through a values-driven approach. The firm is committed to preserving and expanding high-quality businesses, with a strategic focus on stable returns and shareholder value growth. Staple Investments operates primarily in the healthcare, consumer, industrial, and services sectors, employing disciplined private equity strategies to achieve its goals. With a team of approximately 50 experienced professionals, the firm emphasizes operational excellence and rigorous strategy to support its…

Recent Transactions

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Jan 2026 Acquired Corporate Travel Services

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Captivate Partners

1 Total Closed Deal Actively Sourcing Deals

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Captivate Partners is a family-office backed investment private equity firm operating at the intersection of brand and commerce. We are active buyout and growth investors, with a focus on commercial services, business services, multi-site consumer, and platforms that drive next generation commerce.

Recent Transactions

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Sep 2020 Acquired The Paper Store / Uncharted

Enhanced Healthcare Partners

Actively Sourcing Deals

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Enhanced Healthcare Partners is a private equity firm dedicated to investments in the healthcare sector. The firm collaborates with family-run businesses to develop leading healthcare companies, focusing on middle-market healthcare enterprises. With a disciplined strategy for value creation, Enhanced Healthcare Partners targets growth-oriented companies and invests between $25 to $75 million or more in various structures. The firm is committed to building successful healthcare businesses through strategic partnerships and investments.

Recent Transactions

This member has no reported closed transactions.

Republic Funds

Actively Sourcing Deals

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Republic Funds has partnered with entrepreneurs to grow eight service businesses in Canada, the United States and the United Kingdom. We also acquired and improved more than 9,000 apartment units across the U.S. Sun Belt and several commercial and industrial properties across the U.S. Rust Belt. We have acquired controlling and non-controlling stakes in property services companies and other growing businesses including HVAC, Roofing, Fire Protection, Property Management, Pool Service, Dry Cleaning, and Marketing Services.

Recent Transactions

This member has no reported closed transactions.

Third Harbor Partners

Actively Sourcing Deals

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Third Harbor Partners is a New York-based private equity firm investing with committed capital to acquire and build middle market companies across business services and industrials in North America. The firm partners with strong management teams and brings an operationally focused approach to driving long-term value creation.www.thirdharborlp.com

Recent Transactions

This member has no reported closed transactions.

Morgan Stanley Expansion Capital

Actively Sourcing Deals

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Morgan Stanley Expansion Capital is a private investment platform targeting late-stage growth equity and credit investments in technology, healthcare, consumer, digital media and other high-growth sectors.

Recent Transactions

This member has no reported closed transactions.

Clipper Harbor Capital

Actively Sourcing Deals

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Clipper Harbor Capital is a private investment firm dedicated to acquiring and managing assets within complex, operationally intensive sectors. With a strategic focus on real estate, the firm leverages its expertise to navigate and invest in challenging environments such as experiential hospitality, senior living, and behavioral health.

Recent Transactions

This member has no reported closed transactions.

Mosaic Management, LLC

Actively Sourcing Deals

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Mosaic Management is a private equity firm specializing in real estate and platform business investments. The company targets growth investment and operational improvement/enhancement opportunities alongside scalability through acquisition, new location growth, and organic growth. With a long term view and regional focus in the Southeast, Mosaic Management has a proven track record of successful investments through its high focus on 5 investments (3 exited) thus far.

Recent Transactions

This member has no reported closed transactions.

Sway

Actively Sourcing Deals

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As a Managing Director and early-stage venture investor, I have a decade of experience investing across consumer, tech, and media ventures, I’ve led on more than 25 startups, raised capital across multiple fund platforms, and helped shape strategies that merge cultural influence with financial returns.At Sway Media (formerly NEX Cubed VC), I’ve driven firm-wide strategy from rebranding our investment thesis to building the next generation of culturally relevant tech and media ventures. I’ve directed accelerator programming, cultivated relationships with LPs, and co-led…

Recent Transactions

This member has no reported closed transactions.

AAVIN Equity

Actively Sourcing Deals

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Based in Iowa, AAVIN Equity Advisors embodies a 'Main Street' approach to private equity investing. We manage committed funds to deploy capital into established, profitable businesses situated in underserved domestic geographies within the lower segment of the middle market. We specialize in leading buyout and recapitalization transactions of founder- or family-owned businesses, relying on our years of experience and collaborative approach to generate substantial value throughout the investment's lifespan.

Recent Transactions

This member has no reported closed transactions.

Blue Highway Capital

Actively Sourcing Deals

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Blue Highway Capital is a U.S. based investment firm growing small middle market companies nationally, with a focus on the Northeast and Mid-Atlantic regions. We provide $3-12M of growth capital to primarily rural businesses that are at an inflection point. Our firm’s name refers to the backroads on traditional maps and atlases, which were drawn in blue. Providing capital is just a starting point for how we can assist in achieving your vision. Our principals draw from a wealth of sector expertise, personal networks and investment experience to help companies develop growth…

Recent Transactions

This member has no reported closed transactions.

PFM Capital

Actively Sourcing Deals

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Private Equity firm based in Regina, investing in business across Western Canada ranging from EBITDA of $2.0M to $10.0M. Looking for businesses with strong management teams and management looking to invest alongside, within industries with strong sectoral tailwinds.

Recent Transactions

This member has no reported closed transactions.

Momentum Health Partners LLC

Actively Sourcing Deals

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Momentum Health Partners is a private equity platform specializing in healthcare delivery. The firm targets investments in provider-based healthcare platforms, with a particular focus on autism therapy, behavioral health, and post-acute care. Momentum Health Partners seeks scalable, high-growth healthcare specialties that demonstrate strong clinical outcomes and present opportunities for market consolidation. Operating as a private firm, it aims to leverage its expertise to enhance the value and performance of its portfolio companies within the healthcare sector.

Recent Transactions

This member has no reported closed transactions.

Crosslantic Capital

Actively Sourcing Deals

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Institutionally backed private equity firm investing in lower middle market companies across the United States and Europe, with a focus on helping traditional businesses grow through technology, operational expertise, and international expansion.

Recent Transactions

This member has no reported closed transactions.

2717 Partners

Actively Sourcing Deals

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2717 Partners, LP is a limited partnership with a focus on private equity investments, particularly in the technology and healthcare sectors. The firm operates from two primary locations in San Francisco, California, and Greenwich, Connecticut. With a strategic approach towards growth-oriented companies, 2717 Partners has built a robust portfolio comprising 14 companies. As of 2025, the firm employs approximately 150 staff members, reflecting its significant presence in the private equity landscape. The company is committed to fostering innovation and growth within its investment sectors.

Recent Transactions

This member has no reported closed transactions.

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Firms in the Life Sciences Private Equity Funds directory are ordered based on recent deal activity on Axial. The default order reflects observed market signals rather than a subjective ranking of firm quality.

Each profile provides information about the firm’s areas of focus, transaction criteria, and relevant activity on Axial’s M&A platform. Together, these details provide a clearer view of where a firm is active and the types of companies and opportunities most relevant for it.

Based on activity on Axial’s M&A platform, the core revenue range for Life Sciences Private Equity Funds is $3M-$19M, with a core EBITDA range of $800K-$4M. Company size can be an important indicator of fit, as firms often concentrate their experience, resources, and transaction activity within particular segments of the market.

Relevant Life Sciences experience can be an important consideration when evaluating a firm. Familiarity with the sector can provide a stronger understanding of its business models, market dynamics, valuation considerations, and transaction environment. The 219 firms included in this directory provide a starting point for identifying firms with relevant experience and activity in Life Sciences.

Not necessarily. Many firms are active across multiple industries, so inclusion in the Life Sciences Private Equity Funds directory reflects relevant experience or activity in Life Sciences, rather than an exclusive sector focus. Individual profiles provide additional context on each firm’s areas of focus and activity within the sector.

When comparing Private Equity Funds with experience in Life Sciences, consider factors such as size range, geographic reach, and recent transaction activity. These characteristics vary across the 219 firms included in the directory and can help identify firms that align with your needs.

Axial can help you identify and connect with firms based on your objectives and what you are looking to accomplish. The process varies depending on your role and transaction needs. If you are interested in connecting with firms in the Life Sciences Private Equity Funds directory, you can request information here.

Top Life Sciences Private Equity Funds

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